Vitamin B - Long Term Medication

Why certain long-term medication may put you at risk of a Vitamin B deficiency

Vitamin B Deficiency

Long-term medication that is used in the treatment of acid reflux disease results in decreased stomach acid secretion, which in turn can decrease Vitamin B12 absorption and lead to a deficiency thereof1

Vitamin B Deficiency

Other medication such as tablets/capsules used to treat diabetes can also interfere with the absorption of Vitamin B121

What are the benefits of Vitamin B1, B6 and B12?

All three of these B Vitamins help the body to convert the carbohydrates, protein and fats in food into energy that can be used by the body.2,3 They are also important for the maintenance of healthy nerve tissue.2 Other functions include:

Diabetes

Vitamin B1 – maintenance of healthy muscle tissue3

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Vitamin B6 – formation of haemoglobin (substance in red blood cells that transports oxygen around the body) and maintenance of healthy skin 2,3

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Vitamin B12 – formation of red blood cells and DNA (genetic material of cells) 2,3

Symptom checker*

If you have any of the following symptoms, you may have a Vitamin B deficiency. *1-3,5

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What is Neurobion®?

Neurobion® is South Africa’s number 1 Vitamin B treatment.6
Neurobion® Tablets are indicated where a deficiency of the relevant vitamins exist. Neurobion® Tablets contain three B Vitamins:
• 100 mg Vitamin B1 (thiamine)
• 200 mg Vitamin B6 (pyridoxine)
• 200 μg Vitamin B12 (cobalamin)

How do you take Neurobion® tablets?

You may need to take Neurobion® for as long as you are on long-term medication.1

Dosage (30’s)

1 tablet daily

Diabetes

References – Further Reading: 1. da Silva L, McCray S. Vitamin B12: No One Should Be Without It. Pract Gastroenterol 2009:34-46. 2. NHS Choices. Vitamins and minerals – B vitamins and folic acid. [Online] 2012 Nov 26 [cited 2014 Sept 10]. Available from: URL: http://www.nhs.uk/Conditions/vitamins-minerals/Pages/Vitamin-B.aspx. 3. Disorders of Nutrition and Metabolism. Section 11. In: The Merck Manual of Medical Information. Second Edition. (eds) Beers SL, Bowman MA. Pocket Books, New York, London, Toronto, Sydney. Pp 918-926. 4. Merck Manual. Thiamine. [Online] 2012 Dec [cited 2014 Aug 6]. Available from: http://goo.gl/njZp9y. 5. Frye RE, Griffi ng GT. Pyridoxine Deficiency Clinical Presentation. Medscape [Online] 2014 Jan 15 [cited 2014 Aug 6]. Available from: URL: http://emedicine.medscape.com/article/124947-clinical. 6. IMS TPM. August 2015. IMS South Africa.

For full prescribing information refer to the package insert approved by the Medicine Regulatory Authority.

SCHEDULE-1 Neurobion® Tablets. Each tablet contains Vitamin B1 100 mg, Vitamin B6 200 mg and Vitamin B12 200 µg. Reg. No.: H2487 (Act 101/1965). Applicant: Merck (Pty) Ltd. Reg. No.: 1970/004059/07. 1 Friesland Drive, Longmeadow Business Estate South, Modderfontein, South Africa, 1645. Tel: +27 (0) 11 372 5000 / Fax: +27 (0) 11 372 5252. Report adverse events to drug.safety.southeastafrica@merckgroup.com or +27 (0) 11 608 2588 (Fax Line). ZA.NEU.15.10.006 March 2016.

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Vitamin B - Diabetes Support