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Probiotics

Medical References

1. World Health Organisation definition on probiotics 2001 2. ICH. (2003). Harmonised Tripartite Guideline. Stability testing of new drug substances and products Q1A (R2) (Section 2.2.4). Available at: http://www.ich.org/fileadmin/Public_Web_Site/ICH_Products/Guidelines/Quality/Q1A_R2/Step4/Q1A_R2__Guideline.pdf. Published Jan 2017 3. World Gastroenterology Organisation Global Guidelines. Probiotics and Prebiotics. 2017 4. Clinical Guidelines to Probiotic supplementation. Health Canada. 2016 edition Reuterina™ Acute / Reuterina™ Junior / Reuterina™ Daily: Each chew tablet contains a minimum of 1 x 108 live freeze-dried cfu’s of Lactobacillus reuteri Protectis® (Strain DSM 17938) until expiry date. Reuterina™ Femme: Each veg capsule contains 2,5 x 109 cfu’s of Lactobacillus rhamnosus GR-1 and 2,5 x 109 cfu’s of Lactobacillus reuteri RC-14 until expiry date. Reuterina™ Drops: Each 0,2 ml or 5 drops contain a minimum of 1 x 108 live freeze-dried cfu’s of Lactobacillus reuteri Protectis® (Strain DSM 17938) until expiry date. Reuterina™ Vit D: Each 0,2 ml or 5 drops contain a minimum of 1 x 108 live freeze-dried cfu’s of Lactobacillus reuteri Protectis® (Strain DSM 17938) until expiry date and 400IU Vit D3.

Probiotics (good bacteria) antagonise potential pathogens (bad bacteria), improve the intestinal environment, bolster the intestinal barrier, downregulate inflammation, and up-regulate the immune response.

WHAT ARE PROBIOTICS?

WHAT IS A PROBIOTIC?

The World Health Organisation defines probiotics as live micro organisms which, when administered in adequate amounts confers a health benefit on the host.1

The World Gastroenterology Association takes this further by recommending that probiotics have clinical trials on the same strain or combination as contained in the commercial product and at the same dosage as recommended commercially.2

HOW DO PROBIOTICS WORK?

Probiotics (good bacteria) antagonise potential pathogens (bad bacteria), improve the intestinal environment, bolster the intestinal barrier, downregulate inflammation, and up-regulate the immune response.3

WHERE CAN PROBIOTICS HELP?2,3,4

Below is a list of some of the most common areas in which probiotics have been proven to assist:

TREATMENT WITH PROBIOTICS2,3,4

It is important to ensure that the probiotic you choose has clinical evidence in the same strain and dosage as sold commercially. Although most probiotics will balance the microbiota to some extent, the ability to survive through the (GIT) gastrointestinal tract is key to proper functioning and it is therefore important that the probiotic strain or combination should have trials in humans, showing colonisation as well as survivability.

WHAT TO EXPECT?3

Probiotics are live-microorganisms that colonise the human GIT. If the product is not taken preventatively, a few days may be required to see effects of the probiotic (such as a reduction in crying time for colic, relief of constipation and reduction of acute diarrhoea).