Explorer

All Brochures

Videos

BabySense

Yoga

HIV in children – oral pellets

Back to top

New Medicine for children: Lopinavir/Ritonavir Oral Pellets

What is this medicine?

This medicine is Antiretrovirals (ARVs) containing Lopinavir(40mg) and Ritonavir(10mg), they are combined in each pellet1.

It is taken by children living with HIV, who are not able to swallow / who vomit or who don’t like the taste of Lopinavir/Ritonavir syrup or tablets2.

Suitable for children from the age of 6 months2.

The child will be given this medicine with other HIV medicines – Please ask your doctor/nurse about the other medicines.

Important to note:

A capsule is what you will see inside the medicine bottle.

Pellets is what is inside these capsules when you open them.

Do not swallow the capsule whole.

Do not stir, crush or dissolve pellets2.

MUST NOT be broken, crushed, chewed or dissolved3

Back to top

Watch this video for instructions on how to administer the medicine

Back to top

Read and follow the below instructions on how to give the child this medicine when you get home.

You can give this medicine with water, milk or soft food such as porridge, potato or butternut mash or mashed fruits such as bananas.

Back to top

1. How to give the child Oral pellets with milk / drinking water:

STEP 1:

  • Take out the number of capsules the nurse/doctor told you to give the child for 1 dose.
  • Give the required number of capsules one by one.

STEP 2:

  • Hold one capsule up straight with the brown cap at the top and white body at the bottom and then gently tap on top of the capsule for pellets to move to the bottom.
  • Gently twist and pull to open the capsule.

STEP 3:

  • Pour the medicine (pellets) inside the capsule into a spoon.

STEP 4:

  • Add milk / drinking water to the spoon till the spoon fills and feed to the child immediately, to avoid pellets from dissolving.
  • Do not stir, crush or dissolve pellets2.
  • MUST NOT be broken, crushed, chewed or dissolved3

AND REPEAT:

  • Repeat for the prescribed number of capsules. Additional milk / drinking water can be taken after each dose if required.
Back to top

2. How to give Oral pellets with soft food (e.g. porridge or mashed fruit):

  • Prepare porridge / fruit and cool to room temperature.

STEP 2:

  • Take out the number of capsules the nurse/doctor told you to give the child for 1 dose.
  • Give the required number of capsules one by one.

STEP 3:

  • Hold one capsule up straight with the brown cap at the top and white body at the bottom and then gently tap on top of the capsule for pellets to move to the bottom.
  • Gently twist and pull to open the capsule.

STEP 4:

  • Pour the medicine inside the capsule (pellets) into a spoon containing porridge/ fruit and feed to the child immediately, to avoid pellets from dissolving.
  • The porridge / fruit with the medicine should be swallowed immediately and should not be kept for later.
  • Use only a small amount of food to ensure the child swallows all the pellets2.

MUST NOT be broken, crushed, chewed or dissolved3.

AND REPEAT:

  • Repeat this step for the prescribed number of capsules.
  • After giving the milk/water/ soft food with the medicine, give more milk/water/soft food without medicine to make sure that no medicine remains in the mouth.

If you have any questions or you are struggling, please feel free to speak to your nurse or doctor.

Medical References

  1. Cipla Medro (Pty) Ltd. Proposed Annotated Professional Information for Lopimune 40/10 Oral Pellets. www.cipla.co.za (2019).
  2. DoH. Notice: Availability of Lopinavir / Ritonavir Oral Pellets to Children on Antiretroviral Treatment. file:///C:/Users/precious.garnett/Downloads/notice – lopinavir rironavir pellets procurement.pdf (2020).
  3. IATT, UNICEF, W. FACT SHEET ON LOPINAVIR AND RITONAVIR (LPV/R) ORAL PELLETS. https://www.who.int/hiv/pub/toolkits/iatt-factsheet-lopinavir-ritonavir/en/ (2015).
Head
Chest
Abdomen
Pelvis
Legs
Feet
Mental Health
Skin
General
Infant Health

For more health information

Click on the body area you want to know more about. Select a related health topic from the menu

Select a body area

RECENT BROCHURE

HIV in children – oral pellets

Information for patients who have been prescribed oral pellets

RECENT BROCHURE

Asthma – Myths and Facts

The truth about asthma

RECENT BROCHURE

Asthma and Exercise

What you need to know about asthma and exercise:

RECENT BROCHURE

Colds and Flu

Is it just a COLD, or do you have the FLU?

RECENT BROCHURE

COVID-19 – Hand sanitizing correctly

How to sanitize your hands correctly